Bioss Inc.'s Pan Granzyme Polyclonal Antibody, PE Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry. The Pan Granzyme Polyclonal Antibody, PE Conjugated was generated using Granzyme B, and GZMB as the antigen and it reacts with Human, and Mouse.
Description
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis